Discovery of Novel 1-Cyclopentenyl-3-phenylureas as Selective, Brain Penetrant, and Orally Bioavailable CXCR2 Antagonists
Por um escritor misterioso
Last updated 12 abril 2025


Design, synthesis and biological evaluation of novel pyrazolopyrimidone derivatives as potent PDE1 inhibitors - ScienceDirect

WO2014033122A1 - Inhibitors of cd40-traf6 interaction - Google Patents

Sophie GONG, Sr. scientist, GlaxoSmithKline, London, GSK, R&D China

Targeted Treatments for Chronic Obstructive Pulmonary Disease (COPD) Using Low-Molecular-Weight Drugs (LMWDs)

Discovery of Novel 1-Cyclopentenyl-3-phenylureas as Selective, Brain Penetrant, and Orally Bioavailable CXCR2 Antagonists
1-(3-tert-butylsulfonyl-4-cyano-2-hydroxyphenyl)-3 -[(1R)-2-methylcyclopent-2-en-1-yl]urea, C18H23N3O4S

Development of fluorescent peptide G protein‐coupled receptor activation biosensors for NanoBRET characterization of intracellular allosteric modulators - Farmer - 2022 - The FASEB Journal - Wiley Online Library

CXCR2 antagonism promotes oligodendrocyte precursor cell differentiation and enhances remyelination in a mouse model of multiple sclerosis - ScienceDirect

WO2014033122A1 - Inhibitors of cd40-traf6 interaction - Google Patents

CXCR2-IN-2, CXCR2 Antagonist

Design, synthesis and biological evaluation of novel pyrazolopyrimidone derivatives as potent PDE1 inhibitors - ScienceDirect

Discovery of Novel 1-Cyclopentenyl-3-phenylureas as Selective, Brain Penetrant, and Orally Bioavailable CXCR2 Antagonists
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