New Bioshock Game Won't Return To Rapture Or Columbia - GameSpot

Details about Bioshock 4 are thin right now, but a new job listing has thrown out a few crumbs.
BioShock Infinite is a first person shooter where players assume the role of former Pinkerton agent Booker DeWitt who is sent to the flying city of Columbia on a rescue mission to save Elizabeth, who has been imprisoned since childhood.

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Bioshock Infinite: Premium Edition - PC : Video Games