Using origami DNA to trap large viruses

A team of researchers from the Technical University of Munich and the University of Regensburg, both in Germany, has found that it is possible to build origami DNA structures that can be used to trap large viruses. In their paper published in the journal Cell Reports Physical Science, the group describes how they built their structures and how well they worked when tested.

DNA Origami: From Molecular Folding Art to Drug Delivery Technology - Jiang - Advanced Materials - Wiley Online Library

Autonomous DNA molecular motor tailor-designed to navigate DNA origami surface for fast complex motion and advanced nanorobotics

Fabricating higher-order functional DNA origami structures to reveal biological processes at multiple scales

DNA origami traps for large viruses - ScienceDirect

These DNA nanoshells trap a broad spectrum of viruses

Origami” DNA Traps Could Keep Large Viruses From Infecting Cells

Multiple viruses and VLPs trapped in HS-modified O, T1, and T3 shells.

Physics Department, TUM

NGBS2023: Virus traps and other molecular machines of the future - Hendrik Dietz

ISNSCE – International Society for Nanoscale Science, Computation and Engineering

Origami DNA Traps Could Keep Large Viruses From Infecting Cells: by engineering structures out of DNA, scientists could potentially prevent larger viruses, like coronaviruses and influenza viruses, from interacting with cells.

DNA origami traps for large viruses - ScienceDirect

Versatile computer-aided design of free-form DNA nanostructures and assemblies

When the Immune Response Makes COVID-19 Worse