How does SARS-CoV-2 evade the immune defences?

As most of pathogens, SARS-CoV-2 can be recognized by pattern recognition receptors on innate. Normally, this recognition helps the innate immunity to eliminate the infection or to activate the adaptive immune responses, however, SARS-CoV-2 can use its proteins such as M, N, NSP1 and PLpro to interfere with these pathways.

Immune mechanisms underlying COVID-19 pathology and post-acute sequelae of SARS-CoV-2 infection (PASC)

The trinity of COVID-19: immunity, inflammation and intervention

The effects of SARS-CoV-2 infection on modulating innate immunity and strategies of combating inflammatory response for COVID-19 therapy, Journal of Biomedical Science

Neutralization Escape by SARS-CoV-2 Omicron Subvariants BA.2.12.1, BA.4, and BA.5

Cell entry mechanisms of SARS-CoV-2

PEPperPRINT: Webinar: Selection for immune evasion in SARS-CoV-2 revealed by high-resolution epitope mapping combined with genome sequence analysis

Why Subvariants of the SARS-CoV-2 Virus Accelerated the Pandemic

Understanding SARS-CoV-2 antibody binding

The battle between host and SARS-CoV-2: Innate immunity and viral evasion strategies: Molecular Therapy