2′-O methylation of the viral mRNA cap evades host restriction by IFIT family members
Por um escritor misterioso
Last updated 12 abril 2025


N7-Methylation of the Coronavirus RNA Cap Is Required for Maximal Virulence by Preventing Innate Immune Recognition

Ribose 2′-O-methylation provides a molecular signature for the distinction of self and non-self mRNA dependent on the RNA sensor Mda5

Molecular mechanisms of coronavirus RNA capping and methylation

Structure of human IFIT1 with capped RNA reveals adaptable mRNA binding and mechanisms for sensing N1 and N2 ribose 2′-O methylations

Targeting cap1 RNA methyltransferases as an antiviral strategy - ScienceDirect

Frontiers Methyltransferase-Deficient Avian Flaviviruses Are Attenuated Due to Suppression of Viral RNA Translation and Induction of a Higher Innate Immunity

2′-O methylation of the viral mRNA cap evades host restriction by IFIT family members

Frontiers The Emerging Role of RNA Modifications in the Regulation of Antiviral Innate Immunity

Novel insight into the regulatory roles of diverse RNA modifications: Re-defining the bridge between transcription and translation, Molecular Cancer
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